Uso da dupla antiagregação plaquetária em pacientes idosos após síndrome coronariana aguda

Abstract

OBJECTIVE: To analyze the safety profile and effectiveness of the dual antiplatelet therapy in elderly admitted with acute coronary syndrome (ACS) in a cardiology ICU /CCU of the Real Hospital Português (RHP). METHODS: Non-concurrent cohort survey with samples of 165patients older than 65 years old, who were admitted to the cardiology ICU/CCU's RHP from February 2013 to September 2014 with clinical ACS. RESULTS: Of all the subjects studied, 87 were male and 78 female. Among patients diagnosed with ACS, 30.9% attended criteria for unstable angina, 49.7% for AMI without ST segment elevation and 19.4% for AMI with ST elevation. According to CRUSADE score, 44.44% of patients had high or very high chance of bleeding,23.33% had intermediate chance of bleeding and 34.44% had low or very low chance of having bleeding and 78.79% of patients did not have any evidence of bleeding. Of the 34 (20.60%) patients with bleeding, 52,94% were rated minimum, 32,35% were rated lower and 14,70% were rated higher. CONCLUSION: The use of dual antiplatelet therapy in elderly patients after an episode of ACS proved to be safe and effective, the majority of bleeding complications were minimum, without clinical repercussions.